Lyrica (pregabalin) is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Lyrica also affects chemicals in the brain that send pain signals across the nervous system.Lyrica is used to control seizures and to treat fibromyalgia. It is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia, or neuropathic pain associated with spinal cord injury.
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Generic Savella affects certain chemicals in the brain called neurotransmitters. An abnormality in these chemicals is thought to be related to fibromyalgia. Milnacipran is not used to treat depression but how it works in the body is similar to how some antidepressants work. Generic Savella is used to treat a chronic pain disorder called fibromyalgia.
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Regarding the effect: I do notice an increase in bloodflow and a better stamina using the pills (I use 50mg). A side-effect I have noticed is that my nose clogs up so I seem like I have a cold for an hour or so after taking one pill. No other side-effects than that.